Third-generation cephalosporin use is frequently non-guideline-concordant in severe community-acquired pneumonia: Findings from a French critical care cohort

Source: Plos.org· Quitterie Lostie de Kerhor, Zeina Sabouni, Cyrille Geay, Catherine Bouvet-Velly, Laurent Ducros, Jonathan Chelly· July 29, 2026
Third-generation cephalosporin use is frequently non-guideline-concordant in severe community-acquired pneumonia: Findings from a French critical care cohort

Background and objectives Severe community-acquired pneumonia (CAP) remains a major cause of morbidity and mortality, requiring prompt empirical antibiotic therapy. The choice between amoxicillin/clavulanic acid (AMC) and third-generation cephalosporin (3GC) …

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