A nutrient-sensitive enterokine coordinates developmental plasticity through inter-organ signaling

Source: Plos.org· Longwei Bai, Jacques Montagne, Cathy Isaura Ramos, François Leulier· August 11, 2026
A nutrient-sensitive enterokine coordinates developmental plasticity through inter-organ signaling

Animals can modulate the pace of their development in response to nutrient availability, but the underlying mechanisms of this plasticity remain unclear. This study uncovers a nutrient-sensitive gut–brain endocrine circuit that enables developmental adaptatio…

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